Category: Uncategorized
Article or video
Find an article or video that is relevant to this unit. It should not be one that has been covered and not one that is already posted. Then give a sort summary of the article saying why you thought it was interesting. This will count as one reading credit.Your lowest reading quiz will be dropped.
Gender Determination Exercise Summer 2019
Go to
Sex Verification testing of athletes
Go through the case studies of the swimmer and the sprinter. How would you categorize each of them in terms of whether they are “male” or “female”? Explain your answer.
Give your answer in the “leave a reply” section below
Muscular Dystrophy and Medical Ethics Discussion Summer 2018
Read the Mother Courage article and the DIY scientist articles. What major ethical error did a doctor make in the first article? What do you attribute the difference in insight between this doctor and Jill Viles? You will get 2 points for answering this question. You will get 1 point if you comment on someone else’s answer (Give their name), but you must first make a comment before you can read and comment. Note that I must approve the first comment, so you won’t see your comments until after I approve them.
Write your answers as a reply in the comments section
Arthur’s Ancestry Data
I recently had my DNA analyzed by 23 and me. I have decided to share some of these results. Each of the links below has some information about my ancestry or about specific genetic traits. What conclusions can you make from the data? Do you agree with the conclusions?
Ancestry
Most of this is not very surprising. Where might the “Native American” DNA have come from? (Hint read the article belwo)
DNA link from Native Americans to Siberia
Traits
I do not drink coffee. I sometimes drink tea and do drink diet colas.
In middle school I was on the track team and ran distance events. I am not sure I would have done better running sprints.
If I have this, it is rather mild.
I can not taste the strips we used in class on the first day
I don’t have dimples
Student Projects
Author Lauren Colby
Author Brandon Osiwala
Dustbin Game for Replication/Transcription
Author Than Le
Mother Courage Discussion
Read the Mother Courage article and the DIY scientist articles. What major ethical error did a doctor make in the first article? What do you attribute the difference in insight between this doctor and Jill Viles? You will get 2 points for answering this question. You will get 1 point if you comment on someone else’s answer (Give their name), but you must first make a comment before you can read and comment. Note that I must approve the first comment, so you won’t see your comments until after I approve them.
On line Collaborative Worksheet: Basic Human Genetics Problems
All of the material from this site is from the National Library of Medicine (Attributed above)
Instructions
(1): Go to Genetics home reference (Click on the link below)
Genetics Home Reference: Conditions
(2) Using the alphabetical listing find a disease that starts with the first letter of your last name
(3) USING YOUR OWN words, give a brief description of the condition in the comments section. Also give the gene or genes that are thought to be responsible for the condition. Images may be useful. You may post a link to an image, but do not put the image here. Also note these restrictions: https://www.nlm.nih.gov/copyright.html
Note that all information from this website is public domain. Use the information below for use (And see the link on proper citation).
https://ghr.nlm.nih.gov/about/terms-and-conditions
(4) Make a problem based on your disease. You may or may not want to give the inheritance pattern for the condition. For example, one type of problem will be to try to determine the inheritance pattern from the information given.
(5) Note: I have to approve of comments. So you will not see your comment until after I approve. You will also have to register to use this site. Once I have approved your post, I will give you a link to post your answers.
Example
Anonychia congenita
Genetics Home Reference. Bethesda (MD): The Library; Reviewed 2017 May, Cited 2018 January Available from:
https://ghr.nlm.nih.gov/condition/anonychia-congenita
People with this condition are missing fingernails and toenails or only have a portion of these structures.
Attribution:
Anonychia congenita
Genetics Home Reference, National Library of Medicine
https://ghr.nlm.nih.gov/condition/anonychia-congenita
Public domain
Problem: Barry and Sue have normal finger and toe nails as does their son Charlie. Their daughter Chelsea lacks fingernails and toenails.
- Write the genotypes for Barry, Sue and Chelsea.
- What possible genotypes could Charlie have?
- If Barry and Sue have another child, what is the chance that the child has the condition?
Genetic Studies of Chromosomes and Recombination
When scientists first observed chromosomes in mitosis and meiosis, it was suggested that chromosomes were likely to carry the genetic material. Some direct evidence came from studying X linked genes in fruit flies: the traits (such as a trait for eye color) followed the X chromosome. When researchers found genetic evidence for recombination, they wanted to see whether they could correlate physical crossing over on the chromosome withe genetic recombination. In order to do, this scientists took advantage of some characteristics of corn chromosomes.
To understand their research it helps to review a few key corn traits
The colored trait is coded for by a dominant allele (C) and the recessive allele (c) gives yellow kernels
A second gene called Waxy effects the type of starch in the kernels. Wx is a dominant allele that makes 2 kinds of starch (Amylose starch and amylopectin) while corn plants homozygous for the recessive allele (wx) make only amylopectin. The Wx gene and C gene are on chromosome 9 of corn.
Corn chromosomes can also have knobs, which are darkly staining regions at the end of chromosomes. However, for a given chromosome (such as chromosome 9) the knob may or may not be present and it acts like a genetic marker. In other words, a corn plant that has knobs on both chromosome 9s will pass this chromosome to all of its offspring. If such a plant is crossed to a strain that lacks the knob, then the offspring will be heterozygous for the knob trait. Below is a picture of knobs in corn chromosomes. Chromosome Knobs are shown below:
the first critical experiment involved the cross shown below in which plants that were heterozygous for the Knob and the C gene were crossed to plants that lacked the knob and were homozygous for the recessive c allele. These experiments were carried out by Harriet Creighton and Barbara McClintock
From this experiment, the researchers concluded that the chromosome 9 Knob and the C gene were on the same chromosome and linked closely.
The second experiment used a strain of corn that was heterozygous for the Wx gene, the C gene and the knob. Creighton and McClintock carried out the following cross:
In your own words, state what the results of this cross says about the relationship between recombination and physical crossing over.
Image Credits
FIGURE 3. Carmine-stained pachytene chromosomes of the 441123 × 444331 hybrid showing cytologically visible knobs on chromosomes 3(B), 5(C), 6(F), 7(G), 8(I), and 9(J)
From Mondin etal
Karyotype variability in tropical maize sister inbred lines and hybrids compared with KYS standard line
http://journal.frontiersin.org/article/10.3389/fpls.2014.00544/full
Image URL: http://www.frontiersin.org/files/Articles/111039/fpls-05-00544-HTML/image_m/fpls-05-00544-g003.jpg
CCBY
Maize
https://en.wikipedia.org/wiki/Maize
Creative Commons Attribution-ShareAlike License
Maizmorado.png
Malosh
https://commons.wikimedia.org/wiki/File:Maizmorado.png
Creative Commons Attribution-ShareAlike License