Find a video or article on stems cells (including IPS cells) or cloning that you found interesting. Give the URL and a short (1 paragraph) summary of why you found the material interesting. Do use any reading or video that was in this week’s folder and make sure no previous poster use the same source.
Note: because of a time lag delay between when articles are posted and when I approve them, it is possible that 2 more people will use the same source. I will allow this exception to the above rule.
https://www.sciencedaily.com/releases/2009/06/090623091119.htm
i found the material interesting because it was about harvesting stem cells from the placenta as apposed to the umbilical. My mom had stem cells harvested from the umbilical cord when I was born, so that is another reason I found this interesting.
Interesting. That was 10 years ago. Here is a little follow up:
Placental Stem Cells
https://stemcellres.biomedcentral.com/articles/10.1186/s13287-019-1460-1
i found the article to be very interesting because I take an interest in cardiovascular failure and the art of transplantation. This study of adipose stem cells of the heart shows a promising result within their limitation of course that it represent a promising strategy to stimulate spontaneous regeneration and repair in rarefaction areas of the damaged myocardium. The adipose stem cells that were collected showed differnet gene expression and functional capacities that can potentially means that these adipose stem cells can help reduce the progression of heart failure.
http://medprofvideos.mayoclinic.org/videos/mayo-clinic-uses-stem-cell-therapy-to-treat-arthritis-in-knee
I found this article interesting as about half of people over the age of 65 experience arthritis. I have a background in Exercise Science and have trained many people with arthritis in knees and many other areas of the body. When people experience arthritis it often impacts mobility. When we are less mobile, our bodies weaken. If stem cell therapy could aid in diminishing arthritis half of the population over 65 would see these benefits!
https://www.livescience.com/37380-nail-cells-regenerate-lost-fingers.html
I found this article interesting, because during my anatomy class, my professor told us a story of scientist that used stem cell to help regrow his brother’s amputated finger by using stem cell tissue regeneration. However, reading this article shows it has been experimented on mice and amphibians, but not on humans yet. I also read that this tissue stem cell regrowth depends on the area where the amputation occured, if amputation is beneath the stem cell, then there is no growth and also the nerve must be able to sense signal so as to be able to produce protein that promotes tissue growth. This is the future to help the disable become abled again.
Along those lines, you might find this video of interest:
Extra Cellular Matrix and Regeneration
http://www.nytimes.com/video/health/research/100000001773152/extracellular-matrix.html
waow! what an amazing achievement in the world of science. Thank you sir.
https://youtu.be/WwS81bPaZl8
So far every video or article that I have looked at all pretty much said the same basic thing, but the thing that stuck out to me in the particular video is that she also expressed the negative effects of cloning. She pointed out that the only way to harvest the stem cells necessary for cloning was to take them from an embryo, which would prohibit the baby from developing further. In a nut shell it would cost a life to make a clone. She also pointed out in the end that so far any cloned animal that has been produced ended up not being very healthy as naturally born animals. It makes me wonder weather or not this is actually a practice worth preforming.
Most human embryonic stem cell lines come from in vitro fertilized eggs that would not be implanted. Is this really “taking a life”?
https://www.youtube.com/watch?v=vPvToD6kgmE
I found this video interesting on how the professor went about explaining cloning. She drew it out step by step and explained the steps thoroughly. Ips or induced pluripotent stem cells was a tricky topic for me to grasp but the way she explained it helped a lot.
https://www.eurostemcell.org/what-diseases-and-conditions-can-be-treated-stem-cells
This website is a one-stop overview of all things stem cell related. It is a great(!) resource for learning more about how Stem Cell Therapy can be used as treatment for a variety of diseases and conditions. It explains the challenges associated with Stem Cell Therapy, policies and regulations associated, and outlines some clinical trials. One of my favorite tabs to explore were the many valuable resources for a variety of diseases that can be treated (or at least helped) with stem cells. There was also a great video under the “Disease Modeling and Drug Development using Stem Cells” tab.
I chose this as my ex-wife was diagnosed with Multiple Myeloma 3 years ago, she went through autologous transplantation where her own Marrow cells were harvested and reinserted into her body. I remember the call and the short discussion we had when she was diagnosed, I am happy to say the she is now almost (3) three years old ( as my son puts it) and has been in complete remission for this amount of time, she is very healthy and everything seems to have returned to normal. I am an advocate of science as long as its kept into the hands of those that want to do good not evil with it.
https://www.mskcc.org/cancer-care/types/multiple-myeloma/multiple-myeloma-treatment/stem-cell-transplantation
is the linc apparently you are NOT supposed to put the linc in the box provided LOL, if you click my name it will take you to the above link
Thank You!
Hmm I have not seen that as a problem before, but I will check it out. I am glad that your ex-wife is in remission. Stem cells have been very useful for many types of cancer.
https://youtu.be/3YTU0BZM53c
I chose this video because my best friend’s dad was recently diagnosed with Parkinson’s Disease. I have also seen how detrimental Parkinson’s can be in some of my patients I have worked with in Nursing school. I thought this video showed that people are working towards more treatment options for the suffers of Parkinson’s disease. Being diagnosed with Parkinson’s can seem like the end, but with research like this that can change and people can see hope. This treatment uses embryonic stem cells to reproduce the dopamine producing cells that deteriorate during Parkinson’s. Treatment like this could slow the progression of the disease and lessen the symptoms as well. This could be life changing for the people diagnosed with Parkinson’s.
Interesting. That video was from 6 years ago. I wonder how their trials went or even if they have been approved. Some friends of mine have Parkinson’s disease. One is only about 50 years old. He is still functioning well enough, but it is a struggle. Maybe he would be a good test subject for these cells.
https://www.youtube.com/watch?v=mZo1gj6OosY
The use of stem cells for the treatment of Erectile dysfunction. I didn’t really know that stem cells could be used in this way but this video was very informative on why stem cells would work in this type of pathology. It takes stem cells isolated from adipose as well as Platelet Rich Plasma (PLP) taken from blood Is the mixture with stem cells as seeds to regenerate tissue . This will lead to new blood vessels being formed. A really new way to help those feeling down so to say. I think it just goes to show how many versatile ways stem cells can be used.
https://www.medpagetoday.com/publichealthpolicy/healthpolicy/83796
A couple of weeks ago I happened across a podcast called “ Bad Blood” which talked about the use of stem cells to treat a number of conditions under the sun. The podcast went over the fact that treatment with stem cells (except for certain cancer treatments) have not been FDA approved and caused an E. coli. Outbreak and almost killed a number of people. I chose this article because it talks about the company responsible for this outbreak and how the FDA is going about trying to regulate this market and make it safer. Many people hear about stem cells and think it’s a miracle and buy into the gimmick without knowing the science or what they are having injected into their bodies.
The video I chose is on the use of stem cells to help heal burn wounds. I work in the Trauma/Burn ICU where this treatment is not currently used as far as my knowledge, and to see the use of stem cells to help promote and/or accelerate the healing of burns in this video is amazing. The way the stem cells are used to become specialized into skin cells is nothing short of extraordinary. The time it takes to heal a burn is significantly longer than many other wounds and the risk of infection is high and if this treatment were to become more widely used, it would benefit many people who have suffered from a burn.
https://www.cnn.com/videos/health/2016/12/06/new-device-stem-cell-aw-orig-mobile.cnn
https://www.youtube.com/watch?v=jF2iXpoG5j8
I found this video interesting because it gets a lot of great helpful information across in a short amount of time. Watching this video took me back to middle school, watching crash courses and something about the way they illustrate their information makes them such a great learning tool. This video does the same thing, using funny comments and interesting examples, this video tells you the fundamentals about cells and stem cells. It gives you the basic information you need to understand stem cells and what they do.
I found this article to be interesting because it is coming from a Children’s hospital. They article talks about some of the different types of pluripotent stem cells and how each method of collecting cells from different sources creates a cell with slightly different properties. These cells are able to mature into three primary groups of cells: ectoderm, endoderm, and mesoderm. The ectoderm cells give rise to skin and nervous system, endoderm cells form the GI and respiratory tracts, endocrine glands, liver and pancreas, and the mesoderm cells form bone, cartilage, most of the circulatory system, muscles and connective tissue. The article also goes into detail about embryonic stem cells, “true” embryonic stem cells, stem cells made by somatic cell nuclear transfer and stem cells from unfertilized eggs. In the article they mentioned that some people feel that the genetic reprogramming is more ethical than deriving stem cells from embryos or eggs. I think it is amazing that there is a different way to get stem cells that is less controversial.
http://stemcell.childrenshospital.org/about-stem-cells/pluripotent-stem-cells-101/
That is very thorough. I should use it in future classes!
https://www.youtube.com/watch?v=yMmSGt2CNBo
I found this video interesting because it can actually be very helpful in teaching the general public about stem cells. All that I have ever heard about where stem cells come from were from anti-abortion advocates. But this video states that stem cell injections actually a kind of common and they can do it by taking your own stem cells from your bone marrow. I had only ever heard how “stem cells can cure cancer!” and “stem cell research is evil because they are taken from murdered babies!” but if this video from the CDI (Center for Diagnostic Imaging) was more mainstream, it could make stem cell research more widely acceptable.
In 2008 there was a Michigan ballot proposal that allowed for use of human embryonic stem cells in research and in medical procedures. (The proposal passed). Most people do not seem to know that most of these cells come from unused in-vitro fertilized eggs. Another video, provided below by Amalia, fails to mention this important point.
https://www.youtube.com/watch?v=7mLCLx2-dQs
I found this video very interesting because it introduces a possibly improved way of treating a common condition. I think this is a great opportunity to use your own cells as an alternative to adding foreign objects into the body. Avoiding surgery and hospital stays has the potential to decrease risk for infection and possibly reduce healthcare costs. I am interested to see what new research comes from this type of treatment and if it can be used in other joints rather than the knee.
Interesting. One of my fellow instructors recently had stem cell treatment for his knees. I didn’t even know it was common.
This article is about the successful cloning of monkeys in China last year. To me the most interesting part of this is the role that ethics plays in science. They basically say that they have no intentions of using this technology on humans, even though it would be very possible. They state the reason for this as the public not being ready for something like that. It’s funny to me because when I think about science being stunted by public opinion, I generally think of that being a long time ago. Not that I’m advocating for human cloning, but it’s just interesting to me that setbacks like that still exist.
https://www.livescience.com/61516-monkeys-cloned.html
https://youtu.be/9S-xVGsR5Ss
I chose this video sickle cell anemia stem cell transplant because it hits close to home. This family(I do not know them) is originally from Ghana, where I am also originally from. I have very close relatives and friends who battle with the disease almost on a daily basis. I also knew people who lost their battled with the devastating illness and passed. it is very difficult to watch and be able to do nothing when people you care about experience a sickle cell crises. However, this is a success story which I can also relate to as two of my friends children successfully received bone marrow transplants from their siblings(Perfect matches) at the Detroit Children’s hospital Ronald Mcdonald house. Both patients are doing great, both families are elated, and I am excited too. The future is bright.
I chose to search for research that is a little more closer to home than on a national level. Upon searching stem cell research in Michigan, I found that the University of Michigan has reached a milestone in their research with stem cells. They have gotten their stem cell line added to a national registry that can be used by others around the nation for their own research with stem cells. The stem cell line that they registered is from a normal embryo. However, they also have stem cells that carry genetic mutations and will give rise to diseases. The use of these stem cells will help researchers understand diseases better overtime. U of M’s stem cell research program has been making strides to understand disease origins, how to fight Alzheimer’s, and many other areas to put stem cells to use. I think that it is great to know of the work that is happening right here in Michigan.
Video: https://youtu.be/yvCwPdl1Q78
UofM’s stem cell page: http://www.stemcellresearch.umich.edu/
https://www.news-medical.net/news/20191211/Researchers-develop-scar-in-a-dish-model-to-closely-mimic-progressive-organ-scarring.aspx
I found this article to be very interesting because it talks about a use for stem cell research that is a little less direct. It seems like in a lot of cases the stem cells themselves are used to fix a problem or disease directly. In this case they are using the stem cells to mimic an issue, in this case fibrosis, and then resolve it that way. I also like how they mentioned the use of IPS cells as a way for them to create a more accurate model of scarring on organs. In this case stem cells alone weren’t enough to recreate the scarring accurately but the IPS cells gave rise to a multitude of cells needed to create an accurate model. Of course these have all only been trials but it would be interesting to see down the road how this could lead to discovering a medicine necessary for those suffering with fibrosis.
https://www.mdpi.com/1422-0067/20/21/5337/htm
There were many interesting and informative points about stem cells in this article. It delves into the creation of a microenvironment of stem cells and how many aspects of the environment of the extracellular matrix (ECM)determine the roles of the stem cells in regard to differentiation. For example, there are several mechanical properties of the ECM including elastin fibers, GAGsm PGs, fibrous proteins, and fibrillar collagens which guide the interaction of the stimulation from the environment. The article touches on cancer stem cells having a stiff ECM which decreases the activity of the immune system. This makes sense in the increased likelihood of metastasis. Furthermore it touches on the stem cell fate and regeneration which can be determined in some cases by osmotic pressure gradients determining the stimulation of the mesoderm. I also found it interesting to learn the specific roles of particular function of integrins as mediators in directing cells and guiding intracellular protein relations.